Humoral immune responses of tuberculosis patients in Brazil indicate recognition of Mycobacterium tuberculosis MPT-51 and GlcB

被引：11

作者：

Cardoso Almeida, Cristina Melo ^{[1
]}

Vasconcelos, Arioldo C., Jr. ^{[1
]}

Kipnis, Andre ^{[2
]}

Andrade, Ana Lucia ^{[3
]}

Junqueira-Kipnis, Ana Paula ^{[1
]}

机构：

[1] Univ Fed Goias, Dept Microbiol Immunol Parasitol & Patol, Lab Imunopatol Doencas Infecciosas, Goiania, Go, Brazil

[2] Univ Fed Goias, Lab Bacteriol Mol, Goiania, Go, Brazil

[3] Univ Fed Goias, Dept Saude Coletiva, Inst Patol Trop & Saude Publ, Goiania, Go, Brazil

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2008年 / 15卷 / 03期

关键词：

D O I：

10.1128/CVI.00359-07

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

The humoral responses to recombinant MPT-51 and GlcB was determined by using an enzyme-linked immunosorbent assay. Levels of immunoglobulin M (IgM) against MPT-51 and IgG against GlcB were higher among tuberculosis ( TB) patients than among control individuals. When the MPT-51 and GlcB assays were combined, 90.8% specificity and 75.5% sensitivity were observed. MPT-51 and GlcB were recognized in the humoral responses of Brazilian TB patients.

引用

页码：579 / 581

页数：3

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