Methods for the analysis of DNA-protein interactions

被引：33

作者：

Guille, MJ ^{[1
]}

Kneale, GG ^{[1
]}

机构：

[1] UNIV PORTSMOUTH,SCH BIOL SCI,DIV CELL & MOL BIOL,PORTSMOUTH PO1 2DT,HANTS,ENGLAND

来源：

MOLECULAR BIOTECHNOLOGY | 1997年 / 8卷 / 01期

基金：

英国惠康基金; 英国生物技术与生命科学研究理事会;

关键词：

DNA-binding proteins; transcription factors; DNA modification; DNA footprinting;

D O I：

10.1007/BF02762338

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The interaction of proteins with DNA is a central theme of molecular biology. In this article, we review some of the principal techniques currently used for the identification and characterization of DNA binding proteins, and for investigation of the molecular interactions that are responsible for the recognition of specific DNA sequences.

引用

页码：35 / 52

页数：18

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