Evaluation of β-cyclodextrin against natural infections of cryptosporidiosis in calves

被引:13
作者
Castro-Hermida, JA
González-Losada, Y
Freire-Santos, F
Mezo-Menéndez, M
Ares-Mazás, E
机构
[1] Univ Santiago Compostela, Fac Farm, Dept Microbiol & Parasitol, Parasitol Lab, La Coruna 15782, Spain
[2] Ctr Invest Agr Mabegondo, La Coruna, Spain
关键词
Cryptosporidium parvum; cattle-protozoa; beta-cyclodextrin; control methods-protozoa;
D O I
10.1016/S0304-4017(01)00505-2
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The effectiveness of beta -cyclodextrin, excipient used in pharmaceutical industry, in the treatment of natural infection by Ctyptosporidium parvum in suckling calves, was evaluated. Administration of the drug at a dose of 500 mg/kg body weight for 3 consecutive days from birth (prophylactically) or following confirmation of the infection (therapeutically) decreased the severity of diarrhoea and shortened the duration of oocyst shedding. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:85 / 89
页数:5
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