Dominant-negative Rho, Rac, and Cdc42 facilitate the invasion process of Vibrio parahaemolyticus into Caco-2 cells

被引：18

作者：

Akeda, Y

Kodama, T

Kashimoto, T

Cantarelli, V

Horiguchi, Y

Nagayama, K

Iida, T

Honda, T

机构：

[1] Osaka Univ, Res Inst Microbial Dis, Dept Bacterial Infect, Suita, Osaka 5650871, Japan

[2] Osaka Univ, Res Inst Microbial Dis, Dept Bacterial Toxinol, Suita, Osaka 5650871, Japan

[3] Kitasato Univ, Sch Vet Med & Anim Sci, Dept Vet Publ Hlth, Aomori 0348626, Japan

来源：

INFECTION AND IMMUNITY | 2002年 / 70卷 / 02期

关键词：

D O I：

10.1128/IAI.70.2.970-973.2002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To clarify the invasive process of Vibrio parahaemolyticus, an invasion assay was performed using cells expressing dominant negative small GTPases of the Rho family. This assay showed that the dominant negative host phenotype facilitates bacterial invasion, suggesting that the mechanism of V. parahaemolyticus invasion differs from that reported for other invasive bacteria.

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页码：970 / 973

页数：4

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