Synthesis and characterization of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride

被引：193

作者：

Kunishima, M ^{[1
]}

Kawachi, C

Iwasaki, F

Terao, K

Tani, S

机构：

[1] Kobe Gakuin Univ, Fac Pharmaceut Sci, Nishi Ku, Kobe, Hyogo 6512180, Japan

[2] Tokuyama Corp, Tsukuba, Ibaraki 3004247, Japan

[3] Wacker Chem E Asia Ltd, Shinjuku Ku, Tokyo 1690051, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 29期

关键词：

triazines; condensations; amides; carboxylic acids and derivatives;

D O I：

10.1016/S0040-4039(99)00968-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMTMM) was quantitatively synthesized by the coupling of 2-chloro-4,6-methoxy-1,3,9-triazine and N-methylmorpholine in THF, and fully characterized. Condensation of carboxylic acids and amines by DMTMM proceeded effectively in THF to give the corresponding amides in good yield. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：5327 / 5330

页数：4

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