Cell signalling - Calmodulin at the channel gate

被引:27
作者
Ehlers, MD [1 ]
Augustine, GJ [1 ]
机构
[1] Duke Univ, Med Ctr, Dept Neurobiol, Durham, NC 27710 USA
关键词
D O I
10.1038/20079
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
When calcium enters the cell it regulates a host of intracellular signalling processes, including activity of the channels that transported it in there. These voltage-gated Ca2+ channels can be either inactivated or stimulated by Ca2+, and it now turns out that both of these functions are modulated by the same molecule — the classical Ca2+receptor protein calmodulin.
引用
收藏
页码:105 / +
页数:3
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