RAPD: a database of recombinantly-produced antimicrobial peptides

被引：116

作者：

Li, Yifeng ^{[2
]}

Chen, Zhengxin ^{[1
]}

机构：

[1] Univ Nebraska, Dept Comp Sci, Omaha, NE 68182 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Anesthesiol, Los Angeles, CA 90095 USA

来源：

FEMS MICROBIOLOGY LETTERS | 2008年 / 289卷 / 02期

关键词：

antimicrobial peptides; chemical cleavage; database; enzymatic cleavage; fusion expression; recombinant approaches;

D O I：

10.1111/j.1574-6968.2008.01357.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

We have developed the Recombinantly-produced Antimicrobial Peptides Database (RAPD) to house relevant information on recombinant approaches to generate antimicrobial peptides. Key information stored in the database, which is extracted from published experiments, includes expression host, fusion strategy, release method and yield for individual peptides. Bibliographic data directly related to each particular case are also available. RAPD allows easy comparison of the relative popularity and efficiency of different strategies, and can thus be used as a guideline for future production of similar peptides. The database is freely available at http://faculty.ist.unomaha.edu/chen/rapd/index.php.

引用

页码：126 / 129

页数：4

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