Natural killer cells in the innate immunity network of atherosclerosis

被引：40

作者：

Bonaccorsi, Irene ^{[1
,2
]}

De Pasquale, Claudia ^{[1
]}

Campana, Stefania ^{[1
]}

Barberi, Chiara ^{[1
]}

Cavaliere, Riccardo ^{[1
,2
]}

Benedetto, Filippo ^{[3
]}

Ferlazzo, Guido ^{[1
,2
]}

机构：

[1] Univ Messina, Dept Human Pathol, Lab Immunol & Biotherapy, I-98125 Messina, Italy

[2] Univ Hosp AOU Policlin G Martino, Cell Therapy Program, Messina, Italy

[3] Univ Messina, Dept Cardiovasc Surg, Unit Vasc Surg, I-98125 Messina, Italy

来源：

IMMUNOLOGY LETTERS | 2015年 / 168卷 / 01期

关键词：

Natural killer cells; Atherosclerosis; Innate immunity; Macrophages; Dendritic cells; Low density lipoproteins; PLASMACYTOID DENDRITIC CELLS; MONOCYTE CHEMOTACTIC PROTEIN-1; NK-CELLS; IFN-GAMMA; LYMPHOID-CELLS; ACTIVATING RECEPTOR; T-CELLS; INTERFERON; INFLAMMATION; EXPRESSION;

D O I：

10.1016/j.imlet.2015.09.006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Natural killer (NK) cells are innate lymphocytes which have recently been proposed to play an immunoregulatory role in the pathogenesis and progression of atherosclerosis. Although several studies have evaluated the frequency and the functions of NK cells both in human and in experimental animal models of atherosclerosis, it is yet not clear whether NK cells might behave as protective or proatherogenic effectors. Here, we review current knowledge regarding the role of NM cells in atherosclerosis and discuss the potential interactions that might occur in atherosclerotic lesions between NK cells and antigen presenting cells, such as macrophages and dendritic cells. A clearer depiction of the innate immune cell network operating in atherosclerosis might pave the way to novel interesting approaches for the prevention and treatment of this disease. (C) 2015 Elsevier B.V. All rights reserved.

引用

收藏

页码：51 / 57

页数：7

相关论文

共 113 条

[1]

INDUCTION OF NATURAL-KILLER-CELL MIGRATION BY MONOCYTE CHEMOTACTIC PROTEIN-1, PROTEIN-2 AND PROTEIN-3 [J].

ALLAVENA, P ;

BIANCHI, G ;

ZHOU, D ;

VANDAMME, J ;

JILEK, P ;

SOZZANI, S ;

MANTOVANI, A .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1994, 24 (12) :3233-3236

[2]

Divergent signaling pathways regulate IL-12 production induced by different species of Lactobacilli in human dendritic cells [J].

Amar, Yacine ;

Rizzello, Valeria ;

Cavaliere, Riccardo ;

Campana, Stefania ;

De Pasquale, Claudia ;

Barberi, Chiara ;

Oliveri, Daniela ;

Pezzino, Gaetana ;

Costa, Gregorio ;

Meddah, Aicha Tirtouil ;

Ferlazzo, Guido ;

Bonaccorsi, Irene .

IMMUNOLOGY LETTERS, 2015, 166 (01) :6-12

[3]

Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity [J].

Andoniou, CE ;

van Dommelen, SLH ;

Voigt, V ;

Andrews, DM ;

Brizard, G ;

Asselin-Paturel, C ;

Delale, T ;

Stacey, KJ ;

Trinchieri, G ;

Degli-Esposti, MA .

NATURE IMMUNOLOGY, 2005, 6 (10) :1011-1019

[4]

Functional interactions between dendritic cells and NK cells during viral infection [J].

Andrews, DM ;

Scalzo, AA ;

Yokoyama, WM ;

Smyth, MJ ;

Degli-Esposti, MA .

NATURE IMMUNOLOGY, 2003, 4 (02) :175-181

[5]

Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus [J].

Arnon, TI ;

Achdout, H ;

Levi, O ;

Markel, G ;

Saleh, N ;

Katz, G ;

Gazit, R ;

Gonen-Gross, T ;

Hanna, J ;

Nahari, E ;

Porgador, A ;

Honigman, A ;

Plachter, B ;

Mevorach, D ;

Wolf, DG ;

Mandelboim, O .

NATURE IMMUNOLOGY, 2005, 6 (05) :515-523

[6]

Natural killer (NK) cell deficit in coronary artery disease: no aberrations in phenotype but sustained reduction of NK cells is associated with low-grade inflammation [J].

Backteman, K. ;

Ernerudh, J. ;

Jonasson, L. .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2014, 175 (01) :104-112

[7]

Lymphocyte Subpopulations in Lymph Nodes and Peripheral Blood: A Comparison between Patients with Stable Angina and Acute Coronary Syndrome [J].

Backteman, Karin ;

Andersson, Carina ;

Dahlin, Lars-Goran ;

Ernerudh, Jan ;

Jonasson, Lena .

PLOS ONE, 2012, 7 (03)

[8]

Dendritic cells and the control of immunity [J].

Banchereau, J ;

Steinman, RM .

NATURE, 1998, 392 (6673) :245-252

[9]

Activation of NK Cells and T Cells by NKG2D, a Receptor for Stress-Inducible MICA [J].

Bauer, Stefan ;

Groh, Veronika ;

Wu, Jun ;

Steinle, Alexander ;

Phillips, Joseph H. ;

Lanier, Lewis L. ;

Spies, Thomas .

JOURNAL OF IMMUNOLOGY, 2018, 200 (07) :2231-2233

[10]

Identification of a cellular ligand for the natural cytotoxicity receptor NKp44 [J].

Baychelier, Florence ;

Sennepin, Alexis ;

Ermonval, Myriam ;

Dorgham, Karim ;

Debre, Patrice ;

Vieillard, Vincent .

BLOOD, 2013, 122 (17) :2935-2942

← 1 2 3 4 5 6 7 8 9 10 →