Human mesenchymal stem cells and cyclosporin A exert a synergistic suppressive effect on in vitro activation of alloantigen-specific cytotoxic lymphocytes

被引:47
作者
Maccario, R [1 ]
Moretta, A
Cometa, A
Montagna, D
Comoli, P
Locatelli, F
Podestà, M
Frassoni, F
机构
[1] Policlin San Matteo, IRCCS, Lab Transplant Immunol, I-27100 Pavia, Italy
[2] Osped San Martino Genova, Dept Hematol Oncol, Genoa, Italy
关键词
D O I
10.1016/j.bbmt.2005.08.039
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1031 / 1032
页数:2
相关论文
共 6 条
  • [1] Frassoni FLM, 2002, BONE MARROW TRANSPL, V29, P75
  • [2] Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients
    Lazarus, HM
    Koc, ON
    Devine, SM
    Curtin, P
    Maziarz, RT
    Holland, HK
    Shpall, EJ
    McCarthy, P
    Atkinson, K
    Cooper, BW
    Gerson, SL
    Laughlin, MJ
    Loberiza, FR
    Moseley, AB
    Bacigalupo, A
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2005, 11 (05) : 389 - 398
  • [3] Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    Le Blanc, K
    Rasmusson, I
    Sundberg, B
    Götherström, C
    Hassan, M
    Uzunel, M
    Ringdén, O
    [J]. LANCET, 2004, 363 (9419) : 1439 - 1441
  • [4] Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation
    Le Blanc, K
    Ringdén, O
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2005, 11 (05) : 321 - 334
  • [5] Maccario R, 2005, HAEMATOLOGICA, V90, P516
  • [6] Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells
    Rasmusson, I
    Ringdén, O
    Sundberg, B
    Le Blanc, K
    [J]. TRANSPLANTATION, 2003, 76 (08) : 1208 - 1213