Effect of molecular weight and ionic strength on the formation of polyelectrolyte complexes based on poly(methacrylic acid) and chitosan

被引：142

作者：

de Vasconcelos, CL ^{[1
]}

Bezerril, PM ^{[1
]}

dos Santos, DES ^{[1
]}

Dantas, TNC ^{[1
]}

Pereira, MR ^{[1
]}

Fonseca, JLC ^{[1
]}

机构：

[1] Univ Fed Rio Grande Norte, Dept Quim, BR-59078970 Lagoa Nova, RN, Brazil

来源：

BIOMACROMOLECULES | 2006年 / 7卷 / 04期

关键词：

D O I：

10.1021/bm050963w

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chitosan/poly(methacrylic acid) complexes, CS/PMAA, were prepared via dropwise addition of a solution of PMAA to a solution of chitosan in acetic acid 2 wt %. The increase in molecular weight of PMAA inhibited the formation of insoluble complexes, while the increase in ionic strength first favored the formation of the complex followed by inhibiting it at higher concentrations. These observations were related to a description of polyelectrolyte complexation that was strongly dependent on macromolecular dimensions, both in terms of molecular weight and of coil expansion/contraction driven by polyelectrolyte effect.

引用

页码：1245 / 1252

页数：8

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