Chagasic meningoencephalitis in a patient with acquired immunodeficiency syndrome:: Diagnosis, follow-up, and genetic characterization of Trypanosoma cruzi

被引：46

作者：

Lages-Silva, E

Ramirez, LE

Silva-Vergara, ML

Chiari, E

机构：

[1] Univ Fed Minas Gerais, Inst Ciencias Biol, Dept Parasitol, Lab Biol Trypanosoma Cruzi, BR-31270901 Belo Horizonte, MG, Brazil

[2] Fac Med Triangulo Mineiro, Dept Biol Sci, Uberaba, Brazil

[3] Fac Med Triangulo Mineiro, Dept Clin Med, Uberaba, Brazil

来源：

CLINICAL INFECTIOUS DISEASES | 2002年 / 34卷 / 01期

关键词：

D O I：

10.1086/324355

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Early diagnosis of the clinical reactivation of Chagas' disease in human immunodeficiency virus- and Trypanosoma cruzi-coinfected persons is fundamental for a good prognosis. Polymerase chain reaction rapidly and efficiently demonstrated the presence and elimination of T. cruzi in the cerebrospinal fluid of a patient with chagasic meningoencephalitis. Characterization of T. cruzi, directly and indirectly in blood and cerebrospinal fluid samples, demonstrated homogeneity of kinetoplast DNA and the presence of lineage 1 (T. cruzi II) in both parasite populations.

引用

页码：118 / 123

页数：6

共 40 条

[1] Differential tissue distribution of diverse clones of Trypanosoma cruzi in infected mice [J].

Andrade, LO ;

Machado, CRS ;

Chiari, E ;

Pena, SDJ ;

Macedo, AM .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1999, 100 (02) :163-172

[2] POLYMERASE CHAIN-REACTION AMPLIFICATION OF TRYPANOSOMA-CRUZI KINETOPLAST MINICIRCLE DNA ISOLATED FROM WHOLE-BLOOD LYSATES - DIAGNOSIS OF CHRONIC CHAGAS-DISEASE [J].

AVILA, HA ;

SIGMAN, DS ;

COHEN, LM ;

MILLIKAN, RC ;

SIMPSON, L .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1991, 48 (02) :211-221

[3] Different behavior of two Trypanosoma cruzi major clones:: Transmission and circulation in young Bolivian patients [J].

Brenière, SF ;

Bosseno, MF ;

Telleria, J ;

Bastrenta, B ;

Yacsik, N ;

Noireau, F ;

Alcazar, JL ;

Barnabé, C ;

Wincker, P ;

Tibayrenc, M .

EXPERIMENTAL PARASITOLOGY, 1998, 89 (03) :285-295

[4] A SIMPLE PROTOCOL FOR THE PHYSICAL CLEAVAGE OF TRYPANOSOMA-CRUZI KINETOPLAST DNA PRESENT IN BLOOD-SAMPLES AND ITS USE IN POLYMERASE CHAIN-REACTION (PCR)-BASED DIAGNOSIS OF CHRONIC CHAGAS-DISEASE [J].

BRITTO, C ;

CARDOSO, MA ;

WINCKER, P ;

MOREL, CM .

MEMORIAS DO INSTITUTO OSWALDO CRUZ, 1993, 88 (01) :171-172

[5]

CANTAROVICH F, 1992, TRANSPL P, V24, P1902

[6]

Chiari E, 1989, Rev Soc Bras Med Trop, V22, P19, DOI 10.1590/S0037-86821989000100004

[7] Chagas' disease of the cervix uteri in a patient with acquired immunodeficiency syndrome [J].

Concetti, H ;

Retegui, M ;

Pérez, G ;

Pérez, H .

HUMAN PATHOLOGY, 2000, 31 (01) :120-122

[8]

de Diego JA, 1998, TROP MED INT HEALTH, V3, P222

[9] AIDS AND CHAGAS-DISEASE WITH CENTRAL-NERVOUS-SYSTEM TUMOR-LIKE LESION [J].

DELCASTILLO, M ;

MENDOZA, G ;

OVIEDO, J ;

BIANCO, RPP ;

ANSELMO, AE ;

SILVA, M .

AMERICAN JOURNAL OF MEDICINE, 1990, 88 (06) :693-694

[10] Chagas disease and immunosuppression [J].

Ferreira, MS .

MEMORIAS DO INSTITUTO OSWALDO CRUZ, 1999, 94 :325-327

← 1 2 3 4 →