Chagasic meningoencephalitis in a patient with acquired immunodeficiency syndrome:: Diagnosis, follow-up, and genetic characterization of Trypanosoma cruzi

被引：46

作者：

Lages-Silva, E

Ramirez, LE

Silva-Vergara, ML

Chiari, E

机构：

[1] Univ Fed Minas Gerais, Inst Ciencias Biol, Dept Parasitol, Lab Biol Trypanosoma Cruzi, BR-31270901 Belo Horizonte, MG, Brazil

[2] Fac Med Triangulo Mineiro, Dept Biol Sci, Uberaba, Brazil

[3] Fac Med Triangulo Mineiro, Dept Clin Med, Uberaba, Brazil

来源：

CLINICAL INFECTIOUS DISEASES | 2002年 / 34卷 / 01期

关键词：

D O I：

10.1086/324355

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Early diagnosis of the clinical reactivation of Chagas' disease in human immunodeficiency virus- and Trypanosoma cruzi-coinfected persons is fundamental for a good prognosis. Polymerase chain reaction rapidly and efficiently demonstrated the presence and elimination of T. cruzi in the cerebrospinal fluid of a patient with chagasic meningoencephalitis. Characterization of T. cruzi, directly and indirectly in blood and cerebrospinal fluid samples, demonstrated homogeneity of kinetoplast DNA and the presence of lineage 1 (T. cruzi II) in both parasite populations.

引用

页码：118 / 123

页数：6

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