Preparation of spherical and porous chitosan particles by suspension evaporation with O/W/O multiple emulsions

被引：14

作者：

Adachi, T

Ida, J

Wakita, M

Hashimoto, M

Ihara, H

Hirayama, C

机构：

[1] Kurita Water Ind Ltd, Atsugi, Kanagawa 2430124, Japan

[2] Kumamoto Univ, Dept Appl Chem & Biochem, Kumamoto 8608555, Japan

来源：

POLYMER JOURNAL | 1999年 / 31卷 / 04期

关键词：

chitosan; spherical particles; multiple emulsions; microemulsions; suspension evaporation; liquid chromatography;

D O I：

10.1295/polymj.31.319

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Porous spherical particles of chitosan were prepared by conventional suspension evaporation with modification. Aqueous chitosan solution was dispersed in decahydronaphthalene as the suspension medium with a nonionic surfactant as the emulsifier. O/w/o multiple emulsions consisting of aqueous chitosan particles containing decahydronaphthalene and dispersed in decahydronaphthalene were obtained. Chitosan precipitated as insoluble spherical particles by the gradual removal of water with heating. Particle porosity was related to microemulsions formation, the cloud point of the emulsifier and chemical structure of the acid used.

引用

页码：319 / 323

页数：5

共 17 条

[1] MACROPOROUS GLUCOMANNAN SPHERES FOR THE SIZE-EXCLUSION SEPARATION OF AQUEOUS MACROMOLECULES [J].