Adverse reactions after the use of sulphur hexafluoride (SonoVue) echo contrast agent

被引：49

作者：

Geleijnse, Marcel L. ^{[1
]}

Nemes, Attila ^{[1
]}

Vletter, Wim B. ^{[1
]}

Michels, Michelle ^{[1
]}

Soliman, Osama I. I. ^{[1
]}

Caliskan, Kadir ^{[1
]}

Galema, Tjebbe W. ^{[1
]}

ten Cate, Folkert J. ^{[1
]}

机构：

[1] Erasmus Univ, Thoraxctr, Erasmus Med Ctr, NL-3015 GD Rotterdam, Netherlands

来源：

JOURNAL OF CARDIOVASCULAR MEDICINE | 2009年 / 10卷 / 01期

关键词：

adverse reactions; contrast agent; sulphur hexafluoride; ANAPHYLAXIS; COMMITTEE; SAFETY; MEDIA;

D O I：

10.2459/JCM.0b013e328319bfba

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

The aim of the present study was to analyse the adverse effects of SonoVue echo contrast in a consecutive series of 352 cardiac patients during a 4-year period. During 352 consecutive cardiac SonoVue studies, seven patients (2.0%) experienced adverse effects. Four patients (1.1%) had mild allergic reactions causing skin erythema and mild sinus tachycardia, and three patients (0.9%) experienced a severe allergic reaction resulting in (nonfatal) shock. The reported incidence of adverse effects of SonoVue echo contrast in this consecutive series of cardiac patients seems markedly higher than those reported in a company postmarketing analysis.

引用

页码：75 / 77

页数：3

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