The origin of scar-forming kidney myofibroblasts

被引：36

作者：

Eddy, Allison A. ^{[1
]}

机构：

[1] Univ British Columbia, Dept Pediat, Vancouver, BC V6T 1W5, Canada

来源：

NATURE MEDICINE | 2013年 / 19卷 / 08期

关键词：

RENAL FIBROSIS; TISSUE FIBROSIS; BONE-MARROW; FIBROBLASTS; CELLS; DIFFERENTIATE; DEFICIENCY; TRANSITION; MODEL;

D O I：

10.1038/nm.3299

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Whereas diabetes and hypertension predominate as the etiology of chronic kidney disease (CKD), all primary causes share a common progression pathway due to scarring or fibrosis. Understanding what cells are the sources of scar-forming cells is of utmost importance (pages 1047-1053).

引用

页码：964 / 966

页数：3

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