Positron emission tomography for quality assurance of cancer therapy with light ion beams

被引：82

作者：

Enghardt, W. ^{[1
]}

Debus, J. ^{[2
]}

Haberer, T. ^{[3
]}

Hasch, B. G. ^{[1
]}

Hinz, R. ^{[1
]}

Jaekel, O. ^{[2
]}

Kraemer, M. ^{[3
]}

Lauckner, K. ^{[1
]}

Pawelke, J. ^{[1
]}

Poenisch, F. ^{[1
]}

机构：

[1] Forschungszentrum Rossendorf eV, Postfach 510119, D-01314 Dresden, Germany

[2] Deutsch Krebsforschungszentrum, D-69120 Heidelberg, Germany

[3] Gesell Schwerionenforsch mbH, D-64291 Darmstadt, Germany

来源：

NUCLEAR PHYSICS A | 1999年 / 654卷 / 01期

关键词：

D O I：

10.1016/S0375-9474(00)88597-8

中图分类号：

O57 [原子核物理学、高能物理学];

学科分类号：

070202 [粒子物理与原子核物理];

摘要：

Positron emission tomography (PET) offers the possibility of in-situ monitoring the tumour treatment with light ion beams by means of imaging the spatial distribution of beta(+)-activity that is produced as a byproduct of the therapeutic irradiation via nuclear fragmentation reactions between the projectiles and the atomic nuclei of the tissue within the target volume. The implementation of this PET technique at the experimental tumour therapy facility at the Gesellschaft fur Schwerionenforschung (GSI) in Darmstadt and first results of its clinical application are presented.

引用

页码：1047C / 1050C

页数：4

共 14 条

[1]

BEAM LOCALIZATION VIA O-15 ACTIVATION IN PROTON-RADIATION THERAPY [J].

BENNETT, GW ;

GOLDBERG, AC ;

LEVINE, GS ;

GUTHY, J ;

BALSAMO, J ;

ARCHAMBEAU, JO .

NUCLEAR INSTRUMENTS & METHODS, 1975, 125 (03) :333-338

[2]

THE SPATIAL-DISTRIBUTION OF POSITRON-EMITTING NUCLEI GENERATED BY RELATIVISTIC LIGHT-ION BEAMS IN ORGANIC-MATTER [J].

ENGHARDT, W ;

FROMM, WD ;

GEISSEL, H ;

KELLER, H ;

KRAFT, G ;

MAGEL, A ;

MANFRASS, P ;

MUNZENBERG, G ;

NICKEL, F ;

PAWELKE, J ;

SCHARDT, D ;

SCHEIDENBERGER, C ;

SOBIELLA, M .

PHYSICS IN MEDICINE AND BIOLOGY, 1992, 37 (11) :2127-2131

[3]

MAGNETIC SCANNING SYSTEM FOR HEAVY-ION THERAPY [J].

HABERER, T ;

BECHER, W ;

SCHARDT, D ;

KRAFT, G .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1993, 330 (1-2) :296-305

[4]

Hahen R. K. Ten, 1991, MED PHYS, V8, P324

[5]

KANAZAWA M, 1998, P EPAC 98, P2357

[6]

KRAFT G, 1990, STRAHLENTHER ONKOL, V166, P10

[7]

Lauckner K, 1998, Biomed Tech (Berl), V43 Suppl, P28, DOI 10.1515/bmte.1998.43.s1.28

[8]

Llacer J., 1988, Nuclear Science Applications, Section A, V3, P111

[9]

Proton dose monitoring with PET: Quantitative studies in lucite [J].

Oelfke, U ;

Lam, GKY ;

Atkins, MS .

PHYSICS IN MEDICINE AND BIOLOGY, 1996, 41 (01) :177-196

[10]

PROTON THERAPY IN COMBINATION WITH PET AS MONITOR - A FEASIBILITY STUDY [J].

PAANS, AMJ ;

SCHIPPERS, JM .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1993, 40 (04) :1041-1044

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