Mechanistic switch leading to highly efficient chirality transfer in Pd(0)-catalyzed coupling-cyclization of aryl iodides with 1:1 acid-base salts of 2,3-allenoic acids and L-(-)-cinchonidine or D-(+)-/L-(-)-α-methylbenzylamine.: Enantioselective synthesis of highly optically active 3-aryl polysubstituted butenolides

被引：52

作者：

Ma, SM ^{[1
]}

Shi, ZJ ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 05期

关键词：

D O I：

10.1039/b109645a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient methodology provides an easy access to highly optically active polysubstituted butenolides starting from aryl halides and 1:1 salts of optically active 2,3-allenoic acid-base via an oxidative addition-coordinative cyclization-reductive elimination mechanism, which led to the high efficiency of this chirality isomerization reaction.

引用

页码：540 / 541

页数：2

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