Palladium-catalyzed allylation of alkynes with allyl alcohol in aqueous media: Highly regio and stereoselective synthesis of 1,4-dienes

被引：84

作者：

Huang, JM

Zhou, L

Jiang, HF ^{[1
]}

机构：

[1] S China Univ Technol, Coll Chem, Guangzhou 510640, Peoples R China

[2] Chinese Acad Sci, Guangzhou Inst Chem, Guangzhou 510650, Peoples R China

[3] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 12期

关键词：

alkynes; allylation; insertion; palladium; reaction mechanisms;

D O I：

10.1002/anie.200503970

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) The direct approach: The unprecedented result of the title reaction (see scheme) is explained by a mechanism involving competition between π-allylpalladation through cleavage of the C-O bond and the insertion of an alkene. The procedure provides a highly stereo- and regioselective method to construct 1,4-dienes in an economical and environmentally benign manner. © 2006 Wiley-VCH Verlag GmbH S. Co. KGaA.

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页码：1945 / 1949

页数：5

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