A Novel Solvent-Free Approach to Imidazole Containing Nitrogen-Bridgehead Heterocycles

被引：55

作者：

Attanasi, Orazio A. ^{[1
]}

Bianchi, Luca ^{[1
]}

Campisi, Linda A. ^{[1
]}

De Crescentini, Lucia ^{[1
]}

Favi, Gianfranco ^{[1
]}

Mantellini, Fabio ^{[1
]}

机构：

[1] Univ Urbino Carlo Bo, Dept Biomol Sci, Sect Organ Chem & Organ Nat Cpds, I-61029 Urbino, PU, Italy

来源：

ORGANIC LETTERS | 2013年 / 15卷 / 14期

关键词：

ONE-POT SYNTHESIS; AMINOPYRIDINES; DERIVATIVES; FLUORESCENT; AZOALKENES; PYRIDINES; PYRROLES; AFFINITY; LIGANDS; ALPIDEM;

D O I：

10.1021/ol4015267

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A very simple domino reaction under solvent-free conditions of various pyridine-like heterocycles with 1,2-diaza-1,3-dienes produces in good yields imidazo[1,2-a]pyridines, imidazo[1,2-a]quinolines, and imidazo[2,1-a]isoquinolines. The advantage of this one-pot transformation lies in the use of simple pyridine-like compounds without prefunctionalization of the starting heterocycles.

引用

页码：3646 / 3649

页数：4

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