Cortico-cortical interactions in spatial attention: A combined ERP/TMS study

被引：82

作者：

Fuggetta, G

Pavone, EF

Walsh, V

Kiss, M

Eimer, M

机构：

[1] UCL, Inst Cognit Neurosci, London WC1N 3AR, England

[2] UCL, Dept Psychol, London WC1N 3AR, England

[3] Univ London Birkbeck Coll, Dept Psychol, London WC1E 7HX, England

[4] Univ Verona, Dept Neurol & Visual Sci, Sect Neurol Rehabil, I-37100 Verona, Italy

来源：

JOURNAL OF NEUROPHYSIOLOGY | 2006年 / 95卷 / 05期

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

D O I：

10.1152/jn.01273.2005

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

To gain insight into the neural basis of visual attention, we combined transcranial magnetic stimulation (TMS) and event-related potentials (ERPs) during a visual search task. Single-pulse TMS over right posterior parietal cortex (rPPC) delayed response times to targets during conjunction search, and this behavioral effect had a direct ERP correlate. The early phase of the N2pc component that reflects the focusing of attention onto target locations in a search display was eliminated over the right hemisphere when TMS was applied there but was present when TMS was delivered to a control site ( vertex). This finding demonstrates that rPPC TMS interferes with attentional selectivity in remote visual areas.

引用

收藏

页码：3277 / 3280

页数：4

相关论文

共 14 条

[1]

Temporal aspects of visual search studied by transcranial magnetic stimulation [J].

Ashbridge, E ;

Walsh, V ;

Cowey, A .

NEUROPSYCHOLOGIA, 1997, 35 (08) :1121-1131

[2]

The N2pc component as an indicator of attentional selectivity [J].

Eimer, M .

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1996, 99 (03) :225-234

[3]

An exploration of the role of the superior temporal gyrus in visual search and spatial perception using TMS [J].

Ellison, A ;

Schindler, I ;

Pattison, LL ;

Milner, AD .

BRAIN, 2004, 127 :2307-2315

[4]

Timing of right parietal and frontal cortex activity in visuo-spatial perception: a TMS study in normal individuals [J].

Fierro, B ;

Brighina, F ;

Piazza, A ;

Oliveri, M ;

Bisiach, E .

NEUROREPORT, 2001, 12 (11) :2605-2607

[5]

Neural sources of focused attention in visual search [J].

Hopf, JM ;

Luck, SJ ;

Girelli, M ;

Hagner, T ;

Mangun, GR ;

Scheich, H ;

Heinze, HJ .

CEREBRAL CORTEX, 2000, 10 (12) :1233-1241

[6]

SPATIAL-FILTERING DURING VISUAL-SEARCH - EVIDENCE FROM HUMAN ELECTROPHYSIOLOGY [J].

LUCK, SJ ;

HILLYARD, SA .

JOURNAL OF EXPERIMENTAL PSYCHOLOGY-HUMAN PERCEPTION AND PERFORMANCE, 1994, 20 (05) :1000-1014

[7]

Hemispheric asymmetry in visuospatial attention assessed with transcranial magnetic stimulation [J].

Müri, RM ;

Bühler, R ;

Heinemann, D ;

Mosimann, UP ;

Felblinger, J ;

Schlaepfer, TE ;

Hess, CW .

EXPERIMENTAL BRAIN RESEARCH, 2002, 143 (04) :426-430

[8]

Brain activations during visual search: Contributions of search efficiency versus feature binding [J].

Nobre, AC ;

Coull, JT ;

Walsh, V ;

Frith, CD .

NEUROIMAGE, 2003, 18 (01) :91-103

[9]

Three-dimensional probabilistic anatomical cranio-cerebral correlation via the international 10-20 system oriented for transcranial functional brain mapping [J].

Okamoto, M ;

Dan, H ;

Sakamoto, K ;

Takeo, K ;

Shimizu, K ;

Kohno, S ;

Oda, I ;

Isobe, S ;

Suzuki, T ;

Kohyama, K ;

Dan, I .

NEUROIMAGE, 2004, 21 (01) :99-111

[10]

RUSHWORTH MFS, 2005, CEREB CORTEX 1128