Timing of right parietal and frontal cortex activity in visuo-spatial perception: a TMS study in normal individuals

被引:63
作者
Fierro, B
Brighina, F
Piazza, A
Oliveri, M
Bisiach, E
机构
[1] Univ Palermo, Inst Neuropsychiat, Neurophysiol Unit, I-90129 Palermo, Italy
[2] IRCCS S Lucia, Rome, Italy
[3] Univ Turin, Turin, Italy
[4] Univ Palermo, Dept Psychol, Palermo, Italy
关键词
right frontal cortex; right parietal cortex; neglect; TMS; visuo-spatial perception timing;
D O I
10.1097/00001756-200108080-00062
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
In a recent study we showed that repetitive transcranial magnetic stimulation (rTMS) with train duration of 400 ms over right frontal and right posterior parietal cortices gives rise to transitory contralateral visuo-spatial neglect in normal subjects. In the present experiment we investigated whether using single-pulse TMS it is possible to obtain information about the timing of cortical activity related to spatial cognition. Nine healthy subjects performed in baseline condition and during TMS a tachistoscopic task, requiring a forced-choice estimation of the length of the two segments of prebisected horizontal lines. Single-pulse TMS was triggered at various time intervals (150 ms, 225 ms, 300 ms) after visual stimulus onset with a focal coil over P6 and F4 (according to 10/20 EEG system). Relative transitory rightward bias was observed only when parietal TMS was delivered 150ms after visual stimulus presentation. Frontal stimulation induced no effect on visuo-spatial perception with the time intervals explored. NeuroReport 12:2605-2607 (C) 2001 Lippincott Williams & Wilkins.
引用
收藏
页码:2605 / 2607
页数:3
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