Sphingomyelin-cholesterol interactions in biological and model membranes

被引:171
作者
Slotte, JP [1 ]
机构
[1] Abo Akad Univ, Dept Biochem & Pharm, FIN-20521 Turku, Finland
基金
芬兰科学院;
关键词
sphingolipids; sterols; lipid interaction; biological membranes; cell metabolism; lipoproteins; vesicles; monolayers;
D O I
10.1016/S0009-3084(99)00071-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cholesterol and sphingomyelin are both important plasma membrane constituents in cells. It is now becoming evident that these two lipid classes affect each other's metabolism in the cell to an extent that was not previously appreciated. It is the aim of this review to present recent data in the literature concerning both molecular and membrane properties of the two lipid classes, how they interact in membranes (both biological and model), and the consequences their mutual interaction have on different functional and metabolic processes in cells and lipoproteins. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:13 / 27
页数:15
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