Importation and Recombination Are Responsible for the Latest Emergence of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus in China

被引：243

作者：

Zhao, Kuan ^{[1
]}

Ye, Chao ^{[1
]}

Chang, Xiao-Bo ^{[1
]}

Jiang, Cheng-Gang ^{[1
]}

Wang, Shu-Jie ^{[1
]}

Cai, Xue-Hui ^{[1
]}

Tong, Guang-Zhi ^{[2
]}

Tian, Zhi-Jun ^{[1
]}

Shi, Mang ^{[3
,4
]}

An, Tong-Qing ^{[1
]}

机构：

[1] Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Harbin, Peoples R China

[2] Chinese Acad Agr Sci, Shanghai Vet Res Inst, Shanghai, Peoples R China

[3] Univ Sydney, Sch Biol Sci, Charles Perkins Ctr, Marie Bashir Inst Infect Dis & Biosecur, Sydney, NSW 2006, Australia

[4] Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia

来源：

JOURNAL OF VIROLOGY | 2015年 / 89卷 / 20期

基金：

中国国家自然科学基金;

关键词：

VIRULENCE; PRRSV;

D O I：

10.1128/JVI.01446-15

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In China, a majority of the highly pathogenic porcine reproductive and respiratory syndrome (HP-PRRSV) strains were seeded by the 2006 outbreak. However, the most recently emerged (2013-2014) HP-PRRSV strain has a very different genetic background. It is a NADC30-like PRRSV strain recently introduced from North America that has undergone genetic exchange with the classic HP-PRRSV strains in China. Subsequent isolation and characterization of this variant suggest high pathogenicity, so it merits special attention in control and vaccine strategies.

引用

页码：10712 / 10716

页数：5

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