[3H]-M-MPEP, a potent, subtype-selective radioligand for the metabotropic glutamate receptor subtype 5

被引：73

作者：

Gasparini, F ^{[1
]}

Andres, H

Flor, PJ

Heinrich, M

Inderbitzin, W

Lingenhöhl, K

Müller, H

Munk, VC

Omilusik, K

Stierlin, C

Stoehr, N

Vranesic, I

Kuhn, R

机构：

[1] Novartis Pharma AG, Nervous Syst Res, CH-4002 Basel, Switzerland

[2] Novartis Pharma AG, DMPK, Isotope Lab, CH-4002 Basel, Switzerland

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2002年 / 12卷 / 03期

关键词：

D O I：

10.1016/S0960-894X(01)00767-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The synthesis of a new potent, subtype-selective radioligand [H-3]-M-MPEP (2-methyl-6-((3-methoxyphenyl)ethynyl)pyridine) and its in vitro pharmacological characteristics are described. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：407 / 409

页数：3

共 12 条

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