Micro electromagnet for magnetic manipulation in lab-on-a-chip systems

被引:53
作者
Smistrup, K
Tang, PT
Hansen, O
Hansen, MF
机构
[1] Tech Univ Denmark, MIC, Dept Micro & Nanotechnol, DK-2800 Lyngby, Denmark
[2] Tech Univ Denmark, Dept Mfg Engn & Management, DK-2800 Lyngby, Denmark
关键词
magnetic microsystems; separation; microelectromagnets; magnetophoresis;
D O I
10.1016/j.jmmm.2005.05.031
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
We demonstrate a simple scheme for fabrication of microelectromagnets consisting of planar spiral coils semi-encapsulated in soft magnetic yokes using conventional microfabrication techniques. The microelectromagnets are suitable for applications operating at frequencies below 250kHz. Conventional fabrication schemes for planar microelectromagnets typically rely on five mask steps. We allow the current to flow in the soft magnetic yoke and thereby two mask steps are eliminated. We have characterized the electromagnets electrically, the results agree well with theory, and the implications arising from current flowing in the magnetic yoke are discussed. We have integrated the microelectromagnets with microfluidic channels, and demonstrated separation of commercially available magnetic beads from a fluid in a microfluidic system, i.e. a lab-on-a-chip system. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:418 / 426
页数:9
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