Metallo-toeholds: controlling DNA strand displacement driven by Hg(II) ions

被引：40

作者：

Ding, Wei ^{[1
]}

Deng, Wei ^{[1
]}

Zhu, Hong ^{[1
]}

Liang, Haojun ^{[1
,2
]}

机构：

[1] Univ Sci & Technol China, Dept Polymer Sci & Engn, Collaborat Innovat Ctr Chem Energy Mat, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, Peoples R China

[2] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 85期

基金：

中国国家自然科学基金;

关键词：

DUAL-POLARIZATION INTERFEROMETRY; FUELED MOLECULAR MACHINE; LOGIC-GATE OPERATIONS; BASE-PAIRS; REAL-TIME; HG2+; COMPUTATION; MERCURY(II); CASCADES; DUPLEXES;

D O I：

10.1039/c3cc45373a

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Toehold-mediated strand displacement is a powerful tool that permits programmable control over DNA hybridization. Here, we developed a mechanism for strand displacement driven by Hg2+ ions, in which the insertion of thymine-thymine mismatched base pairs on the toeholds provides additional control through variation of the concentration of Hg2+ ions.

引用

收藏

页码：9953 / 9955

页数：3

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