Residential radon exposure and risk of lung cancer in Missouri

被引:106
作者
Alavanja, MCR
Lubin, JH
Mahaffey, JA
Brownson, RC
机构
[1] NCI, Div Can Epidemiol & Genet, Bethesda, MD 20892 USA
[2] Pacific NW Lab, Richland, WA 99352 USA
[3] St Louis Univ, Sch Publ Hlth, Dept Community Hlth, St Louis, MO 63103 USA
关键词
D O I
10.2105/AJPH.89.7.1042
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objectives. This study investigated residential radon exposure and lung I cancer risk, using both standard radon dosimetry and a new radon monitoring technology that, evidence suggests, is a better measure of cumulative radon exposure. Methods. Missouri women (aged 30 to 84 years) newly diagnosed with primary lung cancer during the period January 1, 1993, to January 31, 1994, were invited to participate in this population-based case-control study. Both indoor air radon detectors and CR-39 alpha-particle detectors (surface moni- tors) were used. Results. When surface monitors were used, a significant trend in lung cancer odds ratios was observed for 20-year time-weighted-average radon concentrations. Conclusions. When surface monitors were used, but not when standard radon dosimetry was used, a significant lung cancer risk was found for radon concentrations at and above the action level for mitigation of houses currently used in the United States (148 Bqm(-3)). The risk was below the action level used in Canada (750 Bqm(-3)) and many European countries (200-400 Bqm(-3)).
引用
收藏
页码:1042 / 1048
页数:7
相关论文
共 26 条
[11]  
Koss, 1979, DIAGNOSTIC CYTOLOGY
[12]   LONG-TERM RADON CONCENTRATIONS ESTIMATED FROM PO-210 EMBEDDED IN GLASS [J].
LIVELY, RS ;
STECK, DJ .
HEALTH PHYSICS, 1993, 64 (05) :485-490
[13]   Lung cancer risk from residential radon: Meta-analysis of eight epidemiologic studies [J].
Lubin, JH ;
Boice, JD .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1997, 89 (01) :49-57
[14]   ERRORS IN EXPOSURE ASSESSMENT, STATISTICAL POWER AND THE INTERPRETATION OF RESIDENTIAL RADON STUDIES [J].
LUBIN, JH ;
BOICE, JD ;
SAMET, JM .
RADIATION RESEARCH, 1995, 144 (03) :329-341
[15]   DESIGN ISSUES IN EPIDEMIOLOGIC STUDIES OF INDOOR EXPOSURE TO RN AND RISK OF LUNG-CANCER [J].
LUBIN, JH ;
SAMET, JM ;
WEINBERG, C .
HEALTH PHYSICS, 1990, 59 (06) :807-817
[16]  
Mahaffey JA, 1996, J EXPO ANAL ENV EPID, V6, P425
[17]  
MAHAFFEY JA, IN PRESS RAD PROTECT
[18]  
Radford EP., 1994, NIH PUBLICATION
[19]   RETROSPECTIVE DETERMINATION OF RADON IN HOUSES [J].
SAMUELSSON, C .
NATURE, 1988, 334 (6180) :338-340
[20]   SPATIAL AND TEMPORAL INDOOR RADON VARIATIONS [J].
STECK, DJ .
HEALTH PHYSICS, 1992, 62 (04) :351-355