Cytotoxic activity of some natural and synthetic sesquiterpene lactones

被引：31

作者：

Bruno, M

Rosselli, S

Maggio, A

Raccuglia, RA

Bastow, KF

Wu, CC

Lee, KH

机构：

[1] Univ Palermo, Dipartimento Chim Org Paterno E, I-90128 Palermo, Italy

[2] Univ N Carolina, Sch Pharm, Nat Prod Lab, Chapel Hill, NC USA

来源：

PLANTA MEDICA | 2005年 / 71卷 / 12期

关键词：

D O I：

10.1055/s-2005-873139

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Several natural and synthetic sesquiterpene lactones with different skeletons were tested and found to be active against nine cancer cell lines. Elemane (4), heliangolane (5) and their hydroxy analogues 9 and 10, all containing an alpha,beta-unsaturated aldehyde substituent, were the most potent compounds.

引用

页码：1176 / 1178

页数：3

共 15 条

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[2]

Antibacterial evaluation of cnicin and some natural and semisynthetic analogues [J].