Home Outdoor NO2 and New Onset of Self-Reported Asthma in Adults

被引：57

作者：

Jacquemin, Benedicte ^{[1
,2
]}

Sunyer, Jordi ^{[2
,3
,4
,5
]}

Forsberg, Bertil ^{[6
]}

Aguilera, Inmaculada ^{[2
,3
,4
]}

Briggs, David ^{[7
]}

Garcia-Esteban, Raquel ^{[2
,3
,4
]}

Goetschi, Thomas ^{[8
]}

Heinrich, Joachim ^{[9
]}

Jarvholm, Bengt ^{[6
]}

Jarvis, Debbie ^{[10
]}

Vienneau, Danielle ^{[7
]}

Kuenzli, Nino ^{[2
,3
,4
,11
]}

机构：

[1] INSERM, U780, F-94807 Villejuif, France

[2] Ctr Res Environm Epidemiol CREAL, Barcelona, Spain

[3] IMIM Hosp Mar, Municipal Inst Med Res, Barcelona, Spain

[4] Univ Pompeu Fabra, Dept Hlth & Expt Sci, Barcelona, Spain

[5] CIBERESP, Barcelona, Spain

[6] Umea Univ, Dept Publ Hlth & Clin Med, Umea, Sweden

[7] Univ London Imperial Coll Sci Technol & Med, London, England

[8] Univ So Calif, Dept Prevent Med, Los Angeles, CA 90089 USA

[9] Helmholtz Zentrum Munchen, Inst Epidemiol, Munich, Germany

[10] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, London, England

[11] ICREA, Catalan Inst Res & Adv Studies, Barcelona, Spain

来源：

EPIDEMIOLOGY | 2009年 / 20卷 / 01期

关键词：

AMBIENT AIR-POLLUTION; NITROGEN-DIOXIDE; RESPIRATORY-HEALTH; INHALED ALLERGEN; EXPOSURE; POLLUTANTS; ASSOCIATION; ADMISSIONS; SYMPTOMS; INFECTIONS;

D O I：

10.1097/EDE.0b013e3181886e76

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background: Few studies have investigated new onset of asthma in adults in relation to air pollution. The aim of this study is to investigate the association between modeled background levels of traffic-related air pollution at the subjects' home addresses and self-reported asthma incidence in a European adult population. Methods: Adults from the European Respiratory Health Survey were included (n = 4185 from 17 cities). Subjects' home addresses were geocoded and linked to outdoor nitrogen dioxide (NO,) estimates, as a marker of local traffic-related pollution. We obtained this information from the I-km background NO, surface modeled in APMoSPHERE (Air Pollution Modelling for Support to Policy on Health and Environmental Risk in Europe). Asthma incidence was defined as reporting asthma in the follow-up (1999 to 2001) but not in the baseline (1991 to 1993). Results: A positive association was found between NO, and asthma incidence (odds ratio 1.43; 95% confidence interval = 1.02 to 2.01) per 10 mu g/m(3). Results were homogeneous among centers (P value for heterogeneity = 0.59). Conclusions: We found an association between a marker of traffic-related air pollution and asthma incidence in European adults.

引用

页码：119 / 126

页数：8

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