Autophagic lysosome reformation

被引：128

作者：

Chen, Yang ^{[1
]}

Yu, Li ^{[1
]}

机构：

[1] Tsinghua Univ, Sch Life Sci, State Key Lab Biomembrane & Membrane Biotechnol, Tsinghua Univ Peking Univ Joint Ctr Life Sci, Beijing 100084, Peoples R China

来源：

EXPERIMENTAL CELL RESEARCH | 2013年 / 319卷 / 02期

关键词：

Autophagy; Autophagic lysosome reformation; Lysosome biogenesis; MOLECULAR-MECHANISMS; SELF-DIGESTION; CLATHRIN; SPINSTER; DISEASE; IMMUNITY; MTOR;

D O I：

10.1016/j.yexcr.2012.09.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Autophagy is an evolutionarily conserved lysosome-dependent degradation pathway. In recent years, many important advances have been made in understanding the cellular and molecular mechanism of autophagosome formation. However, the late stages of autophagy-the cellular events after formation of the autolysosome-are relatively rarely studied. In this review, we discussed the cellular process and molecular mechanism of autophagic lysosome reformation, a cellular events which defines the terminal stage of autophagy. (c) 2012 Elsevier Inc. All rights reserved.

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页码：142 / 146

页数：5

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