Synthesis of texaphyrin conjugates

被引:16
作者
Magda, DJ
Wang, Z
Gerasimchuk, N
Wei, WH
Anzenbacher, P
Sessler, JL
机构
[1] Univ Texas, Dept Chem & Biochem, Austin, TX 78712 USA
[2] Pharmacycl Inc, Sunnyvale, CA 94085 USA
关键词
D O I
10.1351/pac200476020365
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This paper summarizes recent synthetic efforts devoted to the generation of new, second-generation texaphyrin-type drugs, specifically species that involve known or potential anticancer agents covalently attached to a tumor-localizing texaphyrin core. Particular emphasis will be placed on the strategies needed to prepare such systems, as well as on the choice of active group being subject to attachment.
引用
收藏
页码:365 / 374
页数:10
相关论文
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