Synthesis of texaphyrin conjugates

被引：16

作者：

Magda, DJ

Wang, Z

Gerasimchuk, N

Wei, WH

Anzenbacher, P

Sessler, JL

机构：

[1] Univ Texas, Dept Chem & Biochem, Austin, TX 78712 USA

[2] Pharmacycl Inc, Sunnyvale, CA 94085 USA

来源：

PURE AND APPLIED CHEMISTRY | 2004年 / 76卷 / 02期

关键词：

D O I：

10.1351/pac200476020365

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This paper summarizes recent synthetic efforts devoted to the generation of new, second-generation texaphyrin-type drugs, specifically species that involve known or potential anticancer agents covalently attached to a tumor-localizing texaphyrin core. Particular emphasis will be placed on the strategies needed to prepare such systems, as well as on the choice of active group being subject to attachment.

引用

页码：365 / 374

页数：10

共 45 条

[1] ADAMS GE, 1980, J NATL CANCER I, V64, P555
[2] *AM CANC SOC, 1999, CANC FACTS FIG 1999
[3] BERLIN V, 1981, J BIOL CHEM, V256, P4747
[4] Blanke CD, 1997, SEMIN ONCOL, V24, P57
[5] BROWN JM, 1981, INT J RADIAT ONCOL, V7, P695
[6] Multicenter phase Ib/II trial of the radiation enhancer motexafin gadolinium in patients with brain metastases
Carde, P
Timmerman, R
Mehta, MP
Koprowski, CD
Ford, J
Tishler, RB
Miles, D
Miller, RA
Renschler, MF
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (07) : 2074 - 2083
[7] CHEN MF, 1995, ANTICANCER RES, V15, P163
[8] GLUTATHIONE EXPORT BY HUMAN LYMPHOID-CELLS - DEPLETION OF GLUTATHIONE BY INHIBITION OF ITS SYNTHESIS DECREASES EXPORT AND INCREASES SENSITIVITY TO IRRADIATION
DETHMERS, JK
MEISTER, A
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (12): : 7492 - 7496
[9] Cellular and molecular aspects of drugs of the future: oxaliplatin
Di Francesco, AM
Ruggiero, A
Riccardi, R
[J]. CELLULAR AND MOLECULAR LIFE SCIENCES, 2002, 59 (11) : 1914 - 1927
[10] Cisplatin-modification of DNA repair and ionizing radiation lethality in yeast, Saccharomyces cerevisiae
Dolling, JA
Boreham, DR
Brown, DL
Raaphorst, GP
Mitchel, REJ
[J]. MUTATION RESEARCH-DNA REPAIR, 1999, 433 (02): : 127 - 136

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