LIVE IMAGING OF EARLY DEVELOPMENTAL PROCESSES IN MAMMALIAN EMBRYOS WITH OPTICAL COHERENCE TOMOGRAPHY

被引：38

作者：

Larin, Kirill V. ^{[1
]}

Larina, Irina V. ^{[2
]}

Liebling, Michael ^{[3
]}

Dickinson, Mary E. ^{[2
]}

机构：

[1] Univ Houston, Dept Biomed Engn, Houston, TX USA

[2] Baylor Coll Med, Dept Mol Physiol & Biophys, Houston, TX 77030 USA

[3] Univ Calif Santa Barbara, Dept Elect & Comp Engn, Santa Barbara, CA 93106 USA

来源：

JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES | 2009年 / 2卷 / 03期

关键词：

Optical Coherence Tomography; non-invasive; mouse embryos; cardiovascular function; DOMAIN MODE-LOCKING; AXIAL SCANS; HIGH-SPEED; HEART; VISUALIZATION; DYNAMICS;

D O I：

10.1142/S1793545809000619

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Early embryonic imaging of cardiovascular development in mammalian models requires a method that can penetrate through and distinguish the many tissue layers with high spatial and temporal resolution. In this paper we evaluate the capability of Optical Coherence Tomography (OCT) technique for structural 3D embryonic imaging in mouse embryos at different stages of the developmental process ranging from 7.5 dpc up to 10.5 dpc. Obtained results suggest that the collected data is suitable for quantitative and qualitative measurements to assess cardiovascular function in mouse models, which is likely to expand our knowledge of the complexity of the embryonic heart, and its development into an adult heart.

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页码：253 / 259

页数：7

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