Bacteria-Adsorbed Palygorskite Stabilizes the Quaternary Phosphonium Salt with Specific-Targeting Capability, Long-Term Antibacterial Activity, and Lower Cytotoxicity

被引：108

作者：

Cai, Xiang ^{[1
]}

Zhang, Jinglin ^{[1
]}

Ouyang, Yu ^{[1
]}

Ma, Dong ^{[2
]}

Tan, Shaozao ^{[1
]}

Peng, Yilong ^{[1
]}

机构：

[1] Jinan Univ, Dept Chem, Guangzhou 510632, Guangdong, Peoples R China

[2] Jinan Univ, Dept Biomed Engn, Guangzhou 510632, Guangdong, Peoples R China

来源：

LANGMUIR | 2013年 / 29卷 / 17期

关键词：

EXCHANGED MONTMORILLONITE; ZNO NANOPARTICLES; ESCHERICHIA-COLI; CLAY-MINERALS; REMOVAL; SILVER; ADSORPTION; COPPER;

D O I：

10.1021/la400824f

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

In order to extend the antibacterial time of quaternary phosphonium salt in bacteria, palygorskite (PGS) is used as the carrier of dodecyl triphenyl phosphonium bromide (DTP), and a DTP-PGS hybrid is prepared. Antibacterial performance of this novel hybrid is investigated for both Gram-positive and Gram-negative bacteria. The results show that the DTP could be absorbed on the surface of PGS which had bacteria-adsorbed capability. The DTP-PGS hybrid, combining the advantages of PGS and DTP, display specific-targeting capability, long-term antibacterial activity, and lower cytotoxicity, suggesting the great potential application as PGS-based antibacterial powder.

引用

收藏

页码：5279 / 5285

页数：7

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