The use of polyethyleneimine-modified reduced graphene oxide as a substrate for silver nanoparticles to produce a material with lower cytotoxicity and long-term antibacterial activity

被引:241
作者
Cai, Xiang [1 ]
Lin, Minsong [1 ]
Tan, Shaozao [1 ]
Mai, Wenjie [2 ,3 ]
Zhang, Yuanming [1 ]
Liang, Zhiwen [2 ,3 ]
Lin, Zhidan [4 ]
Zhang, Xiuju [4 ]
机构
[1] Jinan Univ, Dept Chem, Guangzhou 510632, Guangdong, Peoples R China
[2] Jinan Univ, Dept Phys, Guangzhou 510632, Guangdong, Peoples R China
[3] Jinan Univ, Siyuan Lab, Guangzhou 510632, Guangdong, Peoples R China
[4] Jinan Univ, Dept Mat Sci & Engn, Guangzhou 510632, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
COMPOSITE; RELEASE; TOXICITY; FILMS; WATER;
D O I
10.1016/j.carbon.2012.02.002
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
In order to improve the stability and decrease the cytotoxicity of silver nanoparticle (AgNP), a polyethyleneimine-modified reduced graphene oxide (PEI-rGO) was used as the substrate of AgNPs, and a PEI-rGO-AgNP hybrid was prepared by anchoring the AgNPs on the reduced graphene oxide surface. Such a hybrid showed substantially higher antibacterial activity than polyvinyl pyrrolidone (PVP)-stabilized AgNP, and the AgNPs on PEI-rGO were more stable than the AgNPs on PVP, resulting in long-term antibacterial effects. The hybrid showed excellent water-solubility and lower cytotoxicity, suggesting the great potential application as a sprayable graphene-based antibacterial solution. (C) 2012 Published by Elsevier Ltd.
引用
收藏
页码:3407 / 3415
页数:9
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