The fate of antibiotic resistance marker genes in transgenic plant feed material fed to chickens

被引:42
作者
Chambers, PA
Duggan, PS
Heritage, J [1 ]
Forbes, JM
机构
[1] Univ Leeds, Sch Biochem & Mol Biol, Div Microbiol, Leeds LS2 9JT, W Yorkshire, England
[2] Univ Leeds, Leeds Inst Plant Biotechnol & Agr, Ctr Anim Sci, Leeds LS2 9JT, W Yorkshire, England
关键词
D O I
10.1093/jac/49.1.161
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We have examined the fate of an antibiotic resistance marker, incorporated into transgenic maize when fed to chicks. Plant-derived markers were found in the crops of five birds fed transgenic maize and in the stomach contents of two birds. The plant-derived marker gene was not found in the intestines. The survival of the antibiotic resistance marker gene mirrored that of plant DNA targets, demonstrating that it survives no better than other DNA and indicating that it is very unlikely that bacteria in the gut of chickens will be transformed to ampicillin resistance when the birds are fed transgenic maize.
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页码:161 / 164
页数:4
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