Nationwide Surveillance of Macrolide-Resistant Mycoplasma pneumoniae Infection in Pediatric Patients

被引：117

作者：

Kawai, Yasuhiro ^{[1
]}

Miyashita, Naoyuki ^{[2
]}

Kubo, Mika ^{[1
]}

Akaike, Hiroto ^{[1
]}

Kato, Atsushi ^{[1
]}

Nishizawa, Yoko ^{[1
]}

Saito, Aki ^{[1
]}

Kondo, Eisuke ^{[1
]}

Teranishi, Hideto ^{[1
]}

Wakabayashi, Tokio ^{[1
]}

Ogita, Satoko ^{[1
]}

Tanaka, Takaaki ^{[1
]}

Kawasaki, Kozo ^{[1
]}

Nakano, Takashi ^{[1
]}

Terada, Kihei ^{[1
]}

Ouchi, Kazunobu ^{[1
]}

机构：

[1] Kawasaki Med Sch, Dept Pediat, Okayama, Japan

[2] Kawasaki Med Sch, Dept Internal Med 1, Okayama, Japan

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2013年 / 57卷 / 08期

关键词：

MOLECULAR ANALYSIS; PULMONARY-DISEASE; STRAINS; INTERLEUKIN-18;

D O I：

10.1128/AAC.00663-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We conducted nationwide surveillance to investigate regional differences in macrolide-resistant (MR) Mycoplasma pneumoniae strains in Japan. The prevalence of MR M. pneumoniae in pediatric patients gradually increased between 2008 and 2012. Although regional differences were observed, high levels of MR genes were detected in all seven surveillance areas throughout Japan and ranged in prevalence from 50% to 93%. These regional differences were closely related to the previous administration of macrolides.

引用

收藏

页码：4046 / 4049

页数：4

相关论文

共 24 条

[1]

Averbuch D, 2011, EMERG INFECT DIS, V17, P1079, DOI [10.3201/eid1706.101558, 10.3201/eid/1706.101558]

[2] Emergence of macrolide-resistant strains during an outbreak of Mycoplasma pneumoniae infections in children [J].

Chironna, M. ;

Sallustio, A. ;

Esposito, S. ;

Perulli, M. ;

Chinellato, I. ;

Di Bari, C. ;

Quarto, M. ;

Cardinale, F. .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 (04) :734-737

[3] Occurrence of macrolide-resistant Mycoplasma pneumoniae strains in Germany [J].

Dumke, R. ;

von Baum, H. ;

Lueck, P. C. ;

Jacobs, E. .

CLINICAL MICROBIOLOGY AND INFECTION, 2010, 16 (06) :613-616

[4] Chronic Macrolide Therapy in Inflammatory Airways Diseases [J].

Friedlander, Adam L. ;

Albert, Richard K. .

CHEST, 2010, 138 (05) :1202-1212

[5] Antimicrobial Susceptibility of Mycoplasma pneumoniae Isolates and Molecular Analysis of Macrolide-Resistant Strains from Shanghai, China [J].

Liu, Yang ;

Ye, Xinyu ;

Zhang, Hong ;

Xu, Xiaogang ;

Li, Wanhua ;

Zhu, Demei ;

Wang, Minggui .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (05) :2160-2162

[6] TRANSITION MUTATIONS IN THE 23S RIBOSOMAL-RNA OF ERYTHROMYCIN-RESISTANT ISOLATES OF MYCOPLASMA-PNEUMONIAE [J].

LUCIER, TS ;

HEITZMAN, K ;

LIU, SK ;

HU, PC .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (12) :2770-2773

[7] Characterization and molecular analysis of macrolide-resistant Mycoplasma pneumoniae clinical isolates obtained in Japan [J].

Matsuoka, M ;

Narita, M ;

Okazaki, N ;

Ohya, H ;

Yamazaki, T ;

Ouchi, K ;

Suzuki, I ;

Andoh, T ;

Kenri, T ;

Sasaki, Y ;

Horino, A ;

Shintani, M ;

Arakawa, Y ;

Sasaki, T .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (12) :4624-4630

[8] Clinical potential of diagnostic methods for the rapid diagnosis of Mycoplasma pneumoniae pneumonia in adults [J].

Miyashita, N. ;

Kawai, Y. ;

Yamaguchi, T. ;

Ouchi, K. ;

Oka, M. .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2011, 30 (03) :439-446

[9] Macrolide-resistant Mycoplasma pneumoniae in adolescents with community-acquired pneumonia [J].

Miyashita, Naoyuki ;

Kawai, Yasuhiro ;

Akaike, Hiroto ;

Ouchi, Kazunobu ;

Hayashi, Toshikiyo ;

Kurihara, Takeyuki ;

Okimoto, Niro .

BMC INFECTIOUS DISEASES, 2012, 12

[10] Influence of age on the clinical differentiation of atypical pneumonia in adults [J].

Miyashita, Naoyuki ;

Kawai, Yasuhiro ;

Akaike, Hiroto ;

Ouchi, Kazunobu ;

Hayashi, Toshikiyo ;

Kurihara, Takeyuki ;

Okimoto, Niro .

RESPIROLOGY, 2012, 17 (07) :1073-1079