Sarcopenia in daily practice: assessment and management

被引:657
作者
Beaudart, Charlotte [1 ]
McCloskey, Eugene [2 ,3 ]
Bruyere, Olivier [1 ]
Cesari, Matteo [4 ,5 ]
Rolland, Yves [6 ]
Rizzoli, Rene [7 ]
de Carvalho, Islene Araujo [8 ]
Thiyagarajan, Jotheeswaran Amuthavalli [8 ]
Bautmans, Ivan [9 ]
Bertiere, Marie-Claude [10 ]
Brandi, Maria Luisa [11 ]
Al-Daghri, Nasser M. [12 ]
Burlet, Nansa [1 ]
Cavalier, Etienne [13 ]
Cerreta, Francesca [14 ]
Cherubini, Antonio [15 ]
Fielding, Roger [16 ]
Gielen, Evelien [17 ]
Landi, Francesco [18 ]
Petermans, Jean [19 ]
Reginster, Jean-Yves [1 ]
Visser, Marjolein [20 ,21 ]
Kanis, John [2 ,22 ]
Cooper, Cyrus [23 ,24 ]
机构
[1] Univ Liege, Dept Publ Hlth Epidemiol & Hlth Econ, Ave Hippocrate 13,CHU B23, B-4000 Liege, Belgium
[2] Univ Sheffield, Ctr Metab Bone Dis, Sheffield, S Yorkshire, England
[3] MRC & Arthrit Res UK Ctr Integrated Res Musculosk, London, England
[4] Univ Hosp Toulouse, Gerontopole, Toulouse, France
[5] Univ Toulouse 3, INSERM, UMR1027, Toulouse, France
[6] Univ Toulouse 3, CHU Purpan, Gerontopole Toulouse, Toulouse, France
[7] Univ Hosp Geneva, Fac Med, Serv Bone Dis, Geneva, Switzerland
[8] WHO, Geneva, Switzerland
[9] Vrije Univ Brussel, Gerontol & Frailty Ageing Res Dept, Brussels, Belgium
[10] Ctr Rech & Informat Nutritionnelles, Paris, France
[11] Univ Florence, Dept Surg & Translat Med, Viale Pieraccini 6, I-59139 Florence, Italy
[12] King Saud Univ, Coll Sci, Dept Biochem, Prince Mutaib Chair Biomarkers Osteoporosis, Riyadh 11451, Saudi Arabia
[13] Univ Liege, CHU Sart Tilman, Dept Clin Chem, Bat B35, B-4000 Liege, Belgium
[14] Human Med Res & Dev Support Div, Sci Advice, London, England
[15] IRCCS INRCA, Geriatr & Geriatr Emergency Care, Ancona, Italy
[16] Tufts Univ, Jean Mayer USDA Human Nutr Res Ctr Aging, Nutr Exercise Physiol & Sarcopenia Lab, Boston, MA 02111 USA
[17] Katholieke Univ Leuven, Dept Geriatr Med, Leuven, Belgium
[18] Catholic Univ Sacred Heart Rome, Dept Geriatr Neurosci & Orthoped, Milan, Italy
[19] CHU Sart Tilman, Dept Geriatr, Bat B35, B-4000 Liege, Belgium
[20] Vrije Univ Amsterdam, Dept Hlth Sci, Amsterdam, Netherlands
[21] Vrije Univ Amsterdam, Med Ctr, Dept Nutr & Dietet, Internal Med, Amsterdam, Netherlands
[22] Catholic Univ Australia, Inst Hlth & Aging, Melbourne, Vic, Australia
[23] Univ Southampton, MRC Lifecourse Epidemiol Unit, Southampton, Hants, England
[24] Univ Oxford, NIHR Musculoskeletal Biomed Res Unit, Oxford, England
基金
英国医学研究理事会;
关键词
Sarcopenia; Daily practice; Assessment; Management; Tools; ANTHROPOMETRIC PREDICTION EQUATIONS; BIOELECTRICAL-IMPEDANCE ANALYSIS; APPENDICULAR SKELETAL-MUSCLE; X-RAY ABSORPTIOMETRY; LEAN SOFT-TISSUE; PHYSICAL PERFORMANCE; EUROPEAN-SOCIETY; ECONOMIC-ASPECTS; PROTEIN-INTAKE; VITAMIN-D;
D O I
10.1186/s12877-016-0349-4
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
030301 [社会学]; 100201 [内科学];
摘要
Background: Sarcopenia is increasingly recognized as a correlate of ageing and is associated with increased likelihood of adverse outcomes including falls, fractures, frailty and mortality. Several tools have been recommended to assess muscle mass, muscle strength and physical performance in clinical trials. Whilst these tools have proven to be accurate and reliable in investigational settings, many are not easily applied to daily practice. Methods: This paper is based on literature reviews performed by members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) working group on frailty and sarcopenia. Face-to-face meetings were afterwards organized for the whole group to make amendments and discuss further recommendations. Results: This paper proposes some user-friendly and inexpensive methods that can be used to assess sarcopenia in real-life settings. Healthcare providers, particularly in primary care, should consider an assessment of sarcopenia in individuals at increased risk; suggested tools for assessing risk include the Red Flag Method, the SARC-F questionnaire, the SMI method or different prediction equations. Management of sarcopenia should primarily be patient centered and involve the combination of both resistance and endurance based activity programmes with or without dietary interventions. Development of a number of pharmacological interventions is also in progress. Conclusions: Assessment of sarcopenia in individuals with risk factors, symptoms and/or conditions exposing them to the risk of disability will become particularly important in the near future.
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页码:1 / 10
页数:10
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