Dietary Sources of Lutein and Zeaxanthin Carotenoids and Their Role in Eye Health

被引:359
作者
Abdel-Aal, El-Sayed M. [1 ]
Akhtar, Humayoun [1 ]
Zaheer, Khalid
Ali, Rashida [2 ,3 ]
机构
[1] Agr & Agri Food Canada, Guelph Food Res Ctr, Guelph, ON N1G 5C9, Canada
[2] Univ Karachi, ICCBS, Dept Food Sci & Technol, Karachi 75270, Pakistan
[3] English Biscuit Mfg Pvt Ltd, Korangi Ind Area, Karachi 74900, Pakistan
关键词
lutein and zeaxanthin carotenoids; dietary sources; eye health; high-lutein foods; bioavailability; AGE-RELATED MACULOPATHY; PIGMENT OPTICAL-DENSITY; MACULAR PIGMENT; TISSUE CONCENTRATIONS; SERUM CONCENTRATIONS; ANTIOXIDANT ACTIVITY; VISUAL IMPAIRMENT; NUCLEAR CATARACT; BINDING PROTEIN; PROTECTIVE ROLE;
D O I
10.3390/nu5041169
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 [营养与食品卫生学];
摘要
The eye is a major sensory organ that requires special care for a healthy and productive lifestyle. Numerous studies have identified lutein and zeaxanthin to be essential components for eye health. Lutein and zeaxanthin are carotenoid pigments that impart yellow or orange color to various common foods such as cantaloupe, pasta, corn, carrots, orange/yellow peppers, fish, salmon and eggs. Their role in human health, in particular the health of the eye, is well established from epidemiological, clinical and interventional studies. They constitute the main pigments found in the yellow spot of the human retina which protect the macula from damage by blue light, improve visual acuity and scavenge harmful reactive oxygen species. They have also been linked with reduced risk of age-related macular degeneration (AMD) and cataracts. Research over the past decade has focused on the development of carotenoid-rich foods to boost their intake especially in the elderly population. The aim of this article is to review recent scientific evidences supporting the benefits of lutein and zexanthin in preventing the onset of two major age-related eye diseases with diets rich in these carotenoids. The review also lists major dietary sources of lutein and zeaxanthin and refers to newly developed foods, daily intake, bioavailability and physiological effects in relation to eye health. Examples of the newly developed high-lutein functional foods are also underlined.
引用
收藏
页码:1169 / 1185
页数:17
相关论文
共 99 条
[1]
Abdel-Aal E.-S.M., 2013, AM J BIOMED IN PRESS
[2]
Abdel-Aal E.-S.M., 2013, J CERAL SCI IN PRESS
[3]
Recent advances in the analyses of carotenoids and their role in human health [J].
Abdel-Aal, E-S. M. ;
Akhtar, M. Humayoun .
CURRENT PHARMACEUTICAL ANALYSIS, 2006, 2 (02) :195-204
[4]
Identification and quantification of seed carotenoids in selected wheat species [J].
Abdel-Aal, El-Sayed M. ;
Young, J. Christopher ;
Rabalski, Iwona ;
Hucl, Pierre ;
Fregeau-Reid, Judith .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2007, 55 (03) :787-794
[5]
Stability of Lutein in Wholegrain Bakery Products Naturally High in Lutein or Fortified with Free Lutein [J].
Abdel-Aal, El-Sayed M. ;
Young, J. Christopher ;
Akhtar, Humayoun ;
Rabalski, Iwona .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (18) :10109-10117
[6]
Einkorn:: A potential candidate for developing high lutein wheat [J].
Abdel-Aal, ESM ;
Young, JC ;
Wood, PJ ;
Rabalski, I ;
Hucl, P ;
Falk, D ;
Frégeau-Reid, J .
CEREAL CHEMISTRY, 2002, 79 (03) :455-457
[7]
Phytochemicals and antioxidant activity of milled fractions of different wheat varieties [J].
Adom, KK ;
Sorrells, ME ;
Liu, RH .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (06) :2297-2306
[8]
Metabolism of lutein and zeaxanthin in rhesus monkeys:: Identification of (3R,6′R)- and (3R,6′S)-3′-dehydro-lutein as common metabolites and comparison to humans [J].
Albert, Gesa I. ;
Hoeller, Ulrich ;
Schierle, Joseph ;
Neuringer, Martha ;
Johnson, Elizabeth J. ;
Schalch, Wolfgang .
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 2008, 151 (01) :70-78
[9]
[Anonymous], 2012, Global data on visual impairments 2010
[10]
Prevalence of age-related maculopathy in older Europeans - The European Eye Study (EUREYE) [J].
Augood, CA ;
Vingerling, JR ;
de Jong, PTVM ;
Chakravarthy, U ;
Seland, J ;
Soubrane, G ;
Tomazzoli, L ;
Topouzis, F ;
Bentham, G ;
Rahu, M ;
Vioque, J ;
Young, IS ;
Fletcher, AE .
ARCHIVES OF OPHTHALMOLOGY, 2006, 124 (04) :529-535