neo-Clerodane diterpenoids from Teucrium oliverianum and structure revision of teucrolin E

被引：16

作者：

Al-Yahya, MA

El-Feraly, FS

Dunbar, DC

Muhammad, I ^{[1
]}

机构：

[1] Univ Mississippi, Sch Pharm, Natl Ctr Nat Prod Res, Pharmaceut Sci Res Inst, University, MS 38677 USA

[2] King Saud Univ, Coll Pharm, Dept Pharmacognosy, Riyadh 11451, Saudi Arabia

来源：

PHYTOCHEMISTRY | 2002年 / 59卷 / 04期

关键词：

Teucrium oliverianum; Labiatae; diterpenoids; neo-clerodanes; teucrolins E; F; G; 3; beta; 6 alpha-O-diacetylteucrolin E; 2D NMR;

D O I：

10.1016/S0031-9422(01)00396-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The aerial parts of Teucrium oliverianum yielded two neo-clerodane diterpenoids, teucrolin F and G. together with the known teucrolin E. The previously proposed structure for teucrolin E was revised so that it contains a tetrahydrofuran ring instead of an oxetane ring. This was based on analysis of the NMR spectroscopic data of its diacetate, including its NOE spectra. In addition, the structural assignments of the new diterpenoids were based on H-1 and C-13 NMR spectroscopic studies, mainly 2D NMR experiments, including homonuclear and heteronuclear correlations. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：409 / 414

页数：6

共 18 条

[1]

NEOCLEORDANE DITERPENOIDS AND THEIR ARTIFACTS FROM TEUCRIUM-OLIVARIANUM [J].