InSilico DB genomic datasets hub: an efficient starting point for analyzing genome-wide studies in GenePattern, Integrative Genomics Viewer, and R/Bioconductor

被引：34

作者：

Coletta, Alain ^{[1
]}

Molter, Colin ^{[1
]}

Duque, Robin ^{[1
]}

Steenhoff, David ^{[3
]}

Taminau, Jonatan ^{[3
]}

de Schaetzen, Virginie ^{[3
]}

Meganck, Stijn ^{[3
]}

Lazar, Cosmin ^{[3
]}

Venet, David ^{[1
]}

Detours, Vincent ^{[2
]}

Nowe, Ann ^{[3
]}

Bersini, Hugues ^{[1
]}

Solis, David Y. Weiss ^{[1
]}

机构：

[1] Univ Libre Bruxelles, Inst Rech Interdisciplinaires & Dev Intelligence, Comp & Decis Engn Dept, B-1050 Brussels, Belgium

[2] Univ Libre Bruxelles, IRIBHM, Sch Med, B-1070 Brussels, Belgium

[3] Vrije Univ Brussel, Fac Sci WE, Dept Comp Sci, Computat Modeling Lab CoMo, B-1050 Brussels, Belgium

来源：

GENOME BIOLOGY | 2012年 / 13卷 / 11期

关键词：

GENE-EXPRESSION SIGNATURES; MICROARRAY DATA; REPRODUCIBLE RESEARCH; DATA SETS; CANCER; PROFILES; REVEALS; BIOINFORMATICS; METAANALYSIS; VALIDATION;

D O I：

10.1186/gb-2012-13-11-r104

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Genomics datasets are increasingly useful for gaining biomedical insights, with adoption in the clinic underway. However, multiple hurdles related to data management stand in the way of their efficient large-scale utilization. The solution proposed is a web-based data storage hub. Having clear focus, flexibility and adaptability, InSilico DB seamlessly connects genomics dataset repositories to state-of-the-art and free GUI and command-line data analysis tools. The InSilico DB platform is a powerful collaborative environment, with advanced capabilities for biocuration, dataset sharing, and dataset subsetting and combination. InSilico DB is available from https://insilicodb.org.

引用

页数：13

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