Hydrolysis kinetics of poly(D,L-lactide) monolayers spread on basic or acidic aqueous subphases

被引：47

作者：

Ivanova, T

Panaiotov, I

Boury, F

Proust, JE

Benoit, JP

Verger, R

机构：

[1] UNIV SOFIA,BIOPHYS CHEM LAB,BU-1126 SOFIA,BULGARIA

[2] FAC PHARM ANGERS,F-49100 ANGERS,FRANCE

[3] CNRS,ERS 26,F-13402 MARSEILLE 9,FRANCE

来源：

COLLOIDS AND SURFACES B-BIOINTERFACES | 1997年 / 8卷 / 4-5期

关键词：

hydrolysis; monolayer; poly(D; L-lactide);

D O I：

10.1016/S0927-7765(96)01331-8

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The hydrolysis kinetics of insoluble poly(D,L-lactide) monolayers spread on basic or acidic aqueous substrates was studied with a barostat surface balance. A theoretical approach based on the random fragmentation of polymer molecules leading to the appearance of small soluble fragments was developed. Hydrolysis rate constant values were obtained. The role of interfacial organization of the reaction products is discussed. The process of fragmentation of the interfacial polymer structures was visualized by atomic force microscopy imaging. (C) 1997 Elsevier Science B.V.

引用

页码：217 / 225

页数：9

共 28 条

[21] CHAIN-END SCISSION IN ACID-CATALYZED HYDROLYSIS OF POLY(D,L-LACTIDE) IN SOLUTION [J].