The RNA binding domain of ribosomal protein L11 is structurally similar to homeodomains

被引:63
作者
Xing, YY [1 ]
GuhaThakurta, D [1 ]
Draper, DE [1 ]
机构
[1] JOHNS HOPKINS UNIV,DEPT CHEM,BALTIMORE,MD 21218
关键词
D O I
10.1038/nsb0197-24
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The RNA binding domain of ribosomal protein L11 is strikingly similar to the homeodomain class of eukaryotic DNA binding proteins: it contains three alpha-helices that superimpose with homeodomain alpha-helices, and some conserved residues required for rRNA recognition align with homeodomain helix III residues contacting DNA bases.
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页码:24 / 27
页数:4
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