Solid phase synthesis of quinolones

被引：17

作者：

Srivastava, SK

Haq, W

Murthy, PK

Chauhan, FMS ^{[1
]}

机构：

[1] Cent Drug Res Inst, Div Med Chem, Lucknow 226001, Uttar Pradesh, India

[2] Cent Drug Res Inst, Div Polymers, Lucknow 226001, Uttar Pradesh, India

[3] Cent Drug Res Inst, Div Parasitol, Lucknow 226001, Uttar Pradesh, India

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1999年 / 9卷 / 14期

关键词：

D O I：

10.1016/S0960-894X(99)00326-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Solid phase syntheses of ethyl 6-carboxyquinol-4(1H)-one-3-carboxylate (5) and N-substituted 6-carboxyquinol-4(IH)-one-3-carboxamides 7a-d have been described Antifilarial in vitro activities of 5,7a-d against Brugia malayi have also been delineated. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1885 / 1888

页数：4

共 13 条

[1]

BLACKBURN G, 1997, DRUGS FUTURE, V22, P1007

[2] COLORIMETRIC QUANTITATION OF FILARIAL VIABILITY [J].