Cardiac biomarkers in the prediction of risk in the non-cardiac surgery setting

被引：34

作者：

Biccard, B. M. ^{[1
]}

Devereaux, P. J. ^{[2
]}

Rodseth, R. N. ^{[1
]}

机构：

[1] Univ KwaZulu Natal, Nelson R Mandela Sch Med, Dept Anaesthet, Perioperat Res Grp, Durban, South Africa

[2] McMaster Univ, Dept Clin Epidemiol & Biostat, Hamilton, ON, Canada

来源：

ANAESTHESIA | 2014年 / 69卷 / 05期

关键词：

BRAIN NATRIURETIC PEPTIDE; PERIOPERATIVE MYOCARDIAL-INFARCTION; STRATIFICATION TOOL; VASCULAR-SURGERY; ADVERSE EVENTS; MORTALITY; TROPONIN; OUTCOMES; METAANALYSIS; ASSOCIATION;

D O I：

10.1111/anae.12635

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

B-Type natriuretic peptides and troponin measurements have potential in predicting risk in patients undergoing non-cardiac surgery. Using the American Heart Association framework for the evaluation of novel biomarkers, we review the current evidence supporting the peri-operative use of these two biomarkers. In patients having major non-cardiac surgery who are risk stratified using clinical risk scores, the measurement of natriuretic peptides and troponin, both before and after surgery, significantly improves risk stratification. However, only pre- and postoperative natriuretic peptide measurement and postoperative troponin measurement have shown clinical utility. It is now important for trials to be conducted to determine whether integrating pre- and postoperative natriuretic peptide and postoperative troponin measurement into clinical practice is able to improve clinical outcomes in patients undergoing non-cardiac surgery.

引用

收藏

页码：484 / 493

页数：10

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