Lagunapyrones A-C: Cytotoxic acetogenins of a new skeletal class from a marine sediment bacterium

被引：31

作者：

Lindel, T ^{[1
]}

Jensen, PR ^{[1
]}

Fenical, W ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO,SCRIPPS INST OCEANOG,LA JOLLA,CA 92093

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 09期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0040-4039(96)00014-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The structures of the lagunapyrones A-C (1-3), novel, cytotoxic alpha-pyrones, produced in fermentation by a marine bacterium, have been assigned on the basis of comprehensive spectroscopic analyses. Transformation of lagunapyrone B (2) to its [1', 3'-C-13(2)]-labelled acetonide allowed the relative stereochemistry of the flexible 1,3-diol moiety to be determined.

引用

页码：1327 / 1330

页数：4

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