Recent Advances in Cell-Free PrPSc Amplification Technique

被引:3
作者
Atarashi, Ryuichiro [1 ]
机构
[1] Nagasaki Univ, Grad Sch Biomed Sci, Dept Mol Microbiol & Immunol, Nagasaki 8528523, Japan
关键词
IN-VITRO AMPLIFICATION; RESISTANT PRION PROTEIN; CYCLIC AMPLIFICATION; CONVERSION; BLOOD;
D O I
10.2174/092986609787601697
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The development of amplification technology for abnormal forms of prion protein in vitro has had a great impact on the field of prion research. This novel technology has generated new possibilities for understanding the molecular basis of prions and for developing an early diagnostic test for prion diseases. This review provides an overview of recent progress in cell-free PrPSc amplification techniques.
引用
收藏
页码:256 / 259
页数:4
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