Evidence that Clostridium difficile TcdC is a membrane-associated protein

被引：22

作者：

Govind, Revathi ^{[1
]}

Vediyappan, Govindsamy ^{[1
]}

Rolfe, Rial D. ^{[1
]}

Fralick, Joe A. ^{[1
]}

机构：

[1] Texas Tech Univ, Hlth Sci Ctr, Dept Microbiol & Immunol, Sch Med, Lubbock, TX 79430 USA

来源：

JOURNAL OF BACTERIOLOGY | 2006年 / 188卷 / 10期

关键词：

D O I：

10.1128/JB.188.10.3716-3720.2006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Clostridium difficile produces two toxins, A and B, which act together to cause pseudomembraneous colitis. The genes encoding these toxins, tcdA and tcdB, are part of the pathogenicity locus, which also includes tcdC, a putative negative regulator of the toxin genes. In this study, we demonstrate that TcdC is a membrane-associated protein in C. difficile.

引用

页码：3716 / 3720

页数：5

共 20 条

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