Contemporary diagnosis and management of hypercholesterolemia in elderly acute myocardial infarction patients: A population-based study

被引:6
作者
Berger, Alan K.
Duval, Susan J.
Armstrong, Chris
Jacobs, David R., Jr.
Luepker, Russell V.
机构
[1] Univ Minnesota, Div Epidemiol & Community Hlth, Minneapolis, MN 55454 USA
[2] Univ Minnesota, Sect Cardiovasc Med, Dept Med, Minneapolis, MN 55454 USA
[3] Univ Oslo, Dept Nutr, Oslo, Norway
关键词
D O I
10.1111/j.1076-7460.2007.04886.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
There are limited data regarding the diagnosis and treatment of hypercholesterolemia in elderly patients with acute myocardial infarction (AMI). The authors describe the inhospital and discharge prescription patterns of lipid-lowering agents in patients hospitalized with an AMI, and identify factors associated with low rates of utilization of these therapies. The authors analyzed the Minnesota Heart Survey, a population-based surveillance project that retrospectively abstracted the medical records of patients hospitalized with AMI in 2001-2002 from 21 hospitals in the Minneapolis-St Paul metropolitan area. They identified 2773 patients 30 years and older with an AMI. The mean total cholesterol was 175 45 mg/dL, the mean low-density lipoprotein cholesterol was 104 38 mg/dL, and the mean high-density lipoprotein cholesterol was 44 14 mg/dL. Statins were prescribed at discharge to 74.6%, 63.2%, and 38.5% of patients younger than 65, 65-74, and 75 years and older, respectively (P <.0001). The utilization of statins was highly correlated with the administration of other standard AMI therapies-aspirin, beta-blockers, angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, and reperfusion therapy-and was more prevalent among patients undergoing percutaneous coronary intervention than among those undergoing coronary artery bypass surgery. Elderly patients remain less likely to receive lipid-lowering therapy following an AMI. Greater attention is required to ensure that elderly AMI patients without contraindications are appropriately treated with lipid-lowering therapy.
引用
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页码:15 / 23
页数:9
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