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Integrative analysis of metabolic networks: from peaks to flux models?

被引：9
作者：
Lange, B. Markus
机构：
[1] Washington State Univ, Inst Biol Chem, Pullman, WA 99164 USA
[2] Washington State Univ, Ctr Integrated Biotechnol, Pullman, WA 99164 USA
来源：
CURRENT OPINION IN PLANT BIOLOGY | 2006年 / 9卷 / 03期
基金：
美国国家科学基金会;
关键词：
D O I：
10.1016/j.pbi.2006.03.003
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Recent developments in genomic and post-genomic technologies have led to the amassment of data describing genome sequences, transcript, protein and metabolite abundances, protein modifications, and protein-protein and protein-DNA interactions. Such technologies have vastly expanded the inventory of detectable molecular species and can be used to describe their interdependence, but they have yet to fulfill their promise in enhancing our knowledge of how flux through metabolic pathways is regulated. A convergence of traditional reductionistic and novel holistic experimental approaches could aid in elucidating flux control.
引用
收藏
页码：220 / 226
页数：7
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