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Transcription - Signal transduction and the control of gene expression

被引：483
作者：
Brivanlou, AH
Darnell, JE
机构：
[1] Rockefeller Univ, Mol Cell Biol Lab, New York, NY 10021 USA
[2] Rockefeller Univ, Lab Mol Vertebrate Embryol, New York, NY 10021 USA
来源：
SCIENCE | 2002年 / 295卷 / 5556期
关键词：
D O I：
10.1126/science.1066355
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
More than 2000 transcription factors are encoded in the human genome. Such proteins have often been classified according to common structural elements. But because transcription factors evolved in the service of biologic function, we propose an alternative grouping of eukaryotic transcription factors on the basis of characteristics that describe their roles within cellular regulatory circuits.
引用
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页码：813 / 818
页数：6
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